0.05).Conclusion Combined application of DCSI and acupuncture has a definite effect in improving cerebral ischemia and is superior to that of simple acupuncture or DCSI alone. " />
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Effect of Combined Application of Deproteinised Calf Serum Injection and Acupuncture on Cerebral Ischemia in Rats
Author(s): 
Pages: 9-12
Year: Issue:  1
Journal: Acupuncture Research

Keyword:  Cerebral IschemiaAcupunctureDeproteinised calf serum injection;
Abstract: Objective To study the efficacy of combined application of deproteinised calf serum injection(DCSI) and acupuncture in treating cerebral ischemia(CI) in rats.Methods Ninety Wistar rats were randomly divided into control,CI model,Acupunct(acupuncture),DCSI,Acupunct+DCSI groups,with 18 cases in each group.CI model was duplicated by middle cerebral artery occlusion(MCAO).DCSI(80 mg/kg) was given via the rat's tail vein,once daily for 7 days.Acupuncture was applied to "Baihui"(GV 20),"Shuigou"(GV 26),"Neiguan"(PC 6),"Hegu"(LI 4),"Taichong"(LR 3) and "Zusanli"(ST 36),once daily for 7 days.The neurological deficit score(NDS),cerebral infarct volume(CIV),water and lactic acid(LA) contents in cerebral tissues were measured.Results In comparison with control group,NDS,CIV,cerebral water content and LA in model group increased significantly(P<0.05);while compared with model group,NDS,CIV,cerebral water content and LA in Acupunct,DCSI and Acupunct+DCSI groups decreased significantly(P<0.05).Comparison among DCSI group,Acupunct group and DCSI+Acupunct group showed that NDS,CIV,cerebral water and LA contents of Acupunct+DCSI group were significantly lower than those of the former two groups(P<0.05).No significant differences were found between DCSI and Acupunct groups in the above-mentioned 4 indexes(P>0.05).Conclusion Combined application of DCSI and acupuncture has a definite effect in improving cerebral ischemia and is superior to that of simple acupuncture or DCSI alone.
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