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Latest research progress at home and abroad of pathogenesis of Parkinson\'s disease
Pages: 490-492
Year: Issue:  4
Journal: Occupation and Health

Abstract: 帕金森病(Parkinson’s disease,PD)是一种较为常见的中枢神经系统变性疾病,其病变主要是由于中脑黑质致密部多巴胺(DA)能神经元变性以及残存神经元细胞DA生物合成能力下降从而导致纹状体区DA缺乏引起的.随着社会逐步进入老龄化,PD患者的人数也在日趋增加,但其确切的发病机制迄今尚不十分清楚,PD可能与环境因素、免疫学异常、线粒体功能障碍和氧化应激过度、年龄老化、细胞凋亡等诸多因素有...
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