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Clinical significance of TNF-α level in patients with hand-arm vibration disease
Pages: 180-182
Year: Issue:  4
Journal: Occupational Health and Emergency Rescue

Keyword:  手臂振动病振动性白指肿瘤坏死因子-α;
Abstract: 目的 检测并比较对照组和接振作业人群外周血肿瘤坏死因子-α(TNF-α)水平的差别,探讨其是否适合作为手臂振动病诊断和分级的临床实验室辅助检测指标.方法 酶联免疫吸附法检测目标人群外周血TNF-0水平.结果 94.12%手臂振动病病人(病例组)TNF-α水平超过正常参考值8.1 pg/ml,手臂振动病病人(接振组)TNF-α浓度明显高于对照组(P<0.01).但手臂振动病人中白指组与非白指组及三个不同工龄组间(5年及以下、6~10年、11年及以上)TNF-α水平比较,差异均无统计学意义.结论 手臂振动病病人血中TNF-α异常增高可能与病人血管损伤所致炎症有关,但未呈现出剂量—效应关系趋势.
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