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Characteristics of microRNA and its application in toxicology
Author(s): 
Pages: 186-189
Year: Issue:  4
Journal: Occupational Health and Emergency Rescue

Keyword:  microRNAs肿瘤环境疾病毒理学;
Abstract: MicroRNAs(miRNAs)是一类22 nt左右的小分子非编码单链RNA,它通过与靶mRNA互补结合,调控mRNA翻译,在细胞的生长、分化、发育、代谢和凋亡等活动中发挥作用.研究表明,miRNAs的表达调控着各种肿瘤和环境疾病的发生发展,是一个很好的生物标志,因此miRNAs在毒理学的研究中将会发挥重要作用.
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