The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
AN EVALUATION ON THE EFFECTS OF MORPHINE DOSAGE TITRATION VIA ORAL AND INTRAVENOUS ROUTES FOR THE TREATMENT OF CANCER PAIN
Author(s): 
Pages: 718-722
Year: Issue:  12
Journal: Chinese Journal of Pain Medicine

Keyword:  吗啡滴定癌性疼痛;
Abstract: 目的:探讨阿片类药物治疗癌性疼痛,口服吗啡滴定和静脉吗啡滴定这两种方法的完成时间,不良反应,偏移程度及生活质量的改善情况.方法:两组癌性疼痛患者(n1=n2=30)分别进行口服吗啡滴定和静脉吗啡滴定.记录疼痛缓解程度,生活质量,不良反应,完成时间及偏移程度.结果两种方法均能很好地缓解疼痛,口服和静脉滴定的缓解率[完全缓解(complete remission,CR)+部分缓解(partial remission,PR)]分别达到96.7%和93.3%.口服吗啡滴定在躯体功能(physical function,PF)、角色功能(role function,RF)、情感功能(emotional function,EF)和认知功能(cognitive function,CF)提高率分别为6.8%、13.6%、8.5%和5.3%;静脉吗啡滴定组评分提高率分别为8.5%、13.0%、11.5%和7.7%;口服滴定时不良反应的发生率高于静脉滴定组(P<0.05).口服吗啡滴定完成时间3.7±2.9天,静脉吗啡滴定完成时间2.9±2.3天(P<0.01),平均偏移程度分别是12%和19.2%.结论:口服滴定反应的吗啡消耗量准确,不良反应稍多,完成时间长,提高生活质量稍逊;而静脉滴定则相反.两种滴定方法各有优缺点,可根据患者实际情况选择使用.
Related Articles
No related articles found