The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
xi ning zai jia tu ti nei de yao dai dong li xue
Author(s): 
Pages: 1-3+54
Year: Issue:  5
Journal: Journal of Hygiene Research

Keyword:  矽宁磷光分析法药代动力学;
Abstract: 利用磷光分析法研究了矽宁在家兔体内的药代动力学、生物利用度及血浆蛋白结合率。该法测定生物样品中矽宁含量的灵敏度可达5ng,变异系数为5.57%,平均回收率为83±2%。家兔口服或静注矽宁后,血药浓度-时间的动力学过程符合二室开放式模型。口服给药达峰时间为7.20分钟,表观分布容积较大,组织分布广泛。口服给药的绝对生物利用度为93%。矽宁与小鼠血浆蛋白的结合率为75±2%。
Related Articles
No related articles found