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lv bing xi zai da shu ti nei dai xie chan wu de yan jiu
Author(s): 
Pages: 1-5
Year: Issue:  2
Journal: Journal of Hygiene Research

Keyword:  氯丙烯代谢产物薄层层析肝匀浆烯丙基胆汁雄性大鼠谷胱甘肽提取液乙酸乙醋;
Abstract: 以LD 300mg/kg的剂量,经口给大鼠进行氯丙烯染毒后,从其肝匀浆和胆汁中分离提取氯丙烯的代谢产物并制备了S-烯丙基谷胱甘肽和S-烯丙基半胱氨酸。薄层层析及质谱检测的结果表明,氯丙烯在大鼠体内的主要代谢产物为α-烯丙基谷胱甘肽、S-烯丙基半胱氨酸和另一巯基化合物。此外还可能存在其氧化产物——醛类化合物。
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