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bing bo fen dui jin xing ji xie tong qi bing ren de zhen jing zhi liao xiao guo
Author(s): 
Pages: 819-820
Year: Issue:  7
Journal: Occupation and Health

Keyword:  PropofolMidazolamMechanical ventilationSedation;
Abstract: 目的探讨丙泊酚在机械通气病人中的镇静效果。方法将89例进行机械通气的患者分为丙泊酚组(46例)和咪唑安定组(43例),观测2组患者镇静等级达Ramsay分级3~5级的时间,给药前后呼吸、循环参数的变化,停药后患者清醒时间等指标并进行比较。结果丙泊酚镇静治疗起效快,达到满意镇静深度时间〔(23.46±2.7)min〕优于咪唑安定组〔(31.56±5.3)min〕(t=8.99,P<0.01)用药后血压、心率逐渐稳定,呼吸频率、血氧饱和度、动脉氧分压等亦有明显改善(P<0.05)。丙泊酚停药后清醒时间短〔(22.50±3.8)min〕,与咪唑安定组〔(115.28±5.5)min〕差异有统计学意义(t=91.41,P<0.01)。结论丙泊酚是机械通气患者较理想的的镇静药物。
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