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The inhibition of total glycosides in glaucescent fissistigma root on SGC -7901,S180 and P388 tumor cells
Author(s): 
Pages: 376-378,383
Year: Issue:  7
Journal: Qilu Pharmaceutical Affairs

Keyword:  Total glycosides in glaucescent fissistigma rootAnti - cancerSGC - 7901;
Abstract: Objective To study the effects of total glycosides in glaucescent fissistigma root on SGC - 7901,S180 and P388 tumor cells. Methods To observe the influence of total glycosides in glaucescent fissistigma root to SGC - 7901 human stomach cell by MTT colormetric assay in vitro. The Balb/ c nude mouse was vaccinated SGC - 7901 with tumors had trans-plants,the inhibition of total glycosides in glaucescent fissistigma root on SGC - 7901 was evaluated by the tumor inhibition rate. The KM mouse was vaccinated S180 with subcutaneous vaccination,the inhibition of total glycosides in glaucescent fis-sistigma root on S180 was evaluated by the tumor inhibition rate. The DBA/ 2 mouse was vaccinated P388 with intraperitoneal inoculation,the inhibition of total glycosides in glaucescent fissistigma root on P388 was evaluated by life extension rate. Re-sults Total glycosides in glaucescent fissistigma root can significantly inhibit the SGC - 7901 cell,the tumor growth of SGC- 7901,S180 and P388 in mice. Conclusion Total glycosides in glaucescent fissistigma root had certain anti - cancer activi-ty,it was expected to develop into a new drug from the active fraction of traditional Chinese medicine.
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