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Acid-base balance disorder and prognosis of acute chemical poisoning
Author(s): 
Pages: 405-407+447
Year: Issue:  6
Journal: Occupational Health and Emergency Rescue

Keyword:  acute chemical poisoningacid-base balance disorderprognosisAPACHE II scorehypoxemia;
Abstract: Objective To observe the relationship between prognosis of acute chemical poisoning and acid-base balance disorder among victims. Methods Totally 105 cases of acute chemical poisoning during 1990-2009 were studied retrospectively. The relationship between some indexes such as pH value,PaO2,PaCO2,multiple acid-base balance disorders and prognosis such as death,organ damage and APACHE Ⅱ score was evaluated. Results All dead cases showed the abnormality of pH value,PaO2,or multiple acid-base balance. The cases with abnormality of these indexes had more serious multiple organs damage and their APACHE Ⅱ score showed significant increment. The cases with severer carbon dioxide retention(PaCO2> 6.0 kPa)had more serious multiple organs damage.Conclusion Acute chemical poisoning may cause abnormality of pH,hypoxemia and multiple acid-base balance disorders,which results in severe consequences by affecting prognosis. However,it could provide reference for the early treatment.
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