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Research of extraction and inclusion technology of volatile in Shouwuyizhi Capsules
Pages: 650-652
Year: Issue:  11
Journal: Qilu Pharmaceutical Affairs

Keyword:  Shouwuyizhi CapsulesVolatile oilβ-cyclodextrinInclusion;
Abstract: Objective To optimize the process of volatile oil extraction and β-cyclodextrin( β-CD)inclusion from Fructus Alpiniae Oxyphyllae and Rhizoma Chanxiong in Shouwuyizhi Capsules. Methods Amount of volatile oil was adopted as observation index,and extraction process of volatile oil was optimized by orthogonal test.Inclusion rate of volatile oil and yield of inclusion compound were used as comprehensive assessment parameters to optimize β-CD inclusion technol-ogy and perform inclution validation.Results The optimum extraction process of volatile oil were:water volume of 8 time, extraction time 5 hours;The optimum inclusion technology of volatile oil were:ratio of volatile oil to β-CD was 1: 9,inclu-sion temperature 35 ℃,inclusion time 2 hours.Conclusion The optimized extraction technology had a high rate of oil yield.The optimized inclusion technology was stable,had a high rate of inclusion.The operation method was simple,it can be used as the preparation of volatile oil extraction and inclusion process.
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