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Investigation on drug resistance of staphylococcus aureus in 211 sputum specimens
Author(s): 
Pages: 143-145
Year: Issue:  2
Journal: Occupational Health and Emergency Rescue

Keyword:  临床分布耐药情况金黄色葡萄球菌痰标本MRSAMSSA;
Abstract: [目的]观察分析患者痰标本中金黄色葡萄球菌的临床分布和耐药情况.[方法]随机选取某人民医院的211株痰标本,检测其中是否含有甲氧西林敏感金黄色葡萄球菌(MSSA)与耐甲氧西林金黄色葡萄球菌(MRSA),并对其临床分布与耐药性情况进行观察及分析.[结果]211株痰标本主要来自神经外科、重症医学科与呼吸内科,均检出金黄色葡萄球菌,其中检出MRSA的126株,占59.72%;两种菌对利奈唑胺、万古霉素均不耐药;MRSA对10种抗生素的耐药性高于MSSA,差异有统计学意义(P<0.05).MRSA对于庆大霉素、克林霉素、环丙沙星等药物具有较高的耐药性,MSSA仅对青霉素具有较高的耐药性.同时耐药的抗菌药物包括青霉素、红霉素、克林霉素等.211株菌株中,共150株发生耐多药.[结论]在痰标本中MSSA与MRSA均分布广泛,医院应加强卫生管理,做好消毒工作,以预防感染.
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