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Treatment of toxic encephalopathy caused by 1,2-dichloroethane with edaravone
Author(s): 
Pages: 331-333
Year: Issue:  4
Journal: Occupational Health and Emergency Rescue

Keyword:  12-二氯乙烷中毒性脑病依达拉奉;
Abstract: [目的]观察依达拉奉治疗1,2-二.氯乙烷中毒性脑病的有效性和安全性.[方法]选择38例1,2-二氯乙烷中毒性脑病患者,随机分为依达拉奉治疗组和常规治疗组,治疗组在常规对症治疗的基础上,添加依达拉奉治疗,共治疗2周.对2组患者在治疗前后分别行Glasgow昏迷量表、改良Barthel指数、简易精神状态量表评估,以评定患者病情严重程度,并判断临床疗效.[结果]治疗后治疗组Glasgow昏迷量表、改良Barthel指数、简易精神状态量表评分优于对照组,差异均有统计学意义(P<0.01).治疗组临床有效率为85.0%,高于对照组的55.6%,差异有统计学意义(P<0.05).2组患者均未发生严重不良反应.[结论]依达拉奉治疗1,2-二氯乙烷中毒性脑病有效且安全,可促进患者神经功能恢复,改善认知能力及生活质量,提高临床疗效.
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