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Study on epidemic trends and etiology characteristics of hand, foot and mouth disease in Xi'an City from 2013-2015
Pages: 2515-2517,2521
Year: Issue:  18
Journal: Occupation and Health

Keyword:  Handfoot and mouth diseaseEpidemic trendsEtiology characteristics;
Abstract: [Objective] To analyze the epidemic trends and etiology characteristics of hand,foot and mouth disease (HFMD) in Xi'an City from 2013-2015,provide theoretical basis for the developing related interventions.[Methods] The real-time fluorescent PCR was used to detect the nucleic acid of enterovirus universal type,enterovirus 71(EV71) and Coxsackie virus A16 (CoxA16) in HFMD samples.The epidemiological characteristics and pathogen detection data of HFMD in Xi'an City from 2013-2015 were statistically analyzed with Excel 2007 and SPSS 20.0.[Results] ①The average morbidity of HFMD from 2013-2015 was 287.74/lakh,and the severe cases accounted for 1.24% of the total cases.The male-to-female ratio was 1.41 ∶ 1,and the peak season appeared April to July.The incidence rate in suburban area was high,and the difference in morbidity was statistically significant among different areas(P<0.01).②The pathogen composition of HFMD showed that the other enteroviruses (non-EV71 and non-CoxA16) were the main pathogens in 2013 and 2016,accounting for 66.18% and 51.42% respectively,and EV71 was the dominant pathogen in 2014,accounting for 52.39%.The main pathogen of severe cases was EV71,accounting for 53.69%.[Conclusion] The incidence rate of HFMD is high in Xi'an City,and main pathogen of severe HFMD cases is EV71.The prevention and control strategies should focus on suburban area,and the comprehensive measures (such as controlling source infection,cutting off the transmission) should be taken to reduce the severe cases of HFMD.
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