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bei gen shen jing jie mai chong she pin lian he lian xu she pin zhi liao xiong duan dai zhuang zuo zhen hou shen jing tong
Author(s): 
Pages: 69-72
Year: Issue:  1
Journal: Chinese Journal of Pain Medicine

Abstract: 带状疱疹后神经痛 (postherpetic neuralgia, PHN) 是急性带状疱疹愈合后1个月仍持续存在的一种疼痛,为带状疱疹最常见的并发症,我国PHN的发病率为9%~34% [1],其治疗以药物为基础,常结合微创介入治疗、射频治疗等方法.射频治疗模式包括连续射频(continuous radiofrequency, CRF) 和脉冲射频 (pulsed radiofrequency, PRF) .PRF 临床较为常用,因其不引起神经改变,可避免对痛觉和触觉纤维造成热凝损伤,疼痛缓解效果好,并发症和不良反应较少.缺点是镇痛效果持续时间短,不少病人需反复治疗;而CRF易导致不可逆的神经损伤,治疗后虽然疼痛缓解时间长,但并发症和不良反应相对较多 [2,3].因此,理想的方法是既能延长镇痛效果,又能减少治疗相关不良反应,从而提升对PHN的疗效,使病人获益.为此,本研究团队通过查阅国内外文献,发现国外有学者利用常规PRF (42℃~45℃) 联合CRF (60℃~65℃) 治疗其他部位的神经性疼痛,效果满意且并发症少或轻微 [4~6],本研究在目前CRF和PRF技术成熟应用的基础上,将常规PRF 联合45℃ CRF 用于治疗胸段PHN,探讨其疗效和安全性.
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