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Protective Effect of HSP70 in U87 Cell Line Treated with Dimethoate
Author(s): 
Pages: 171-174
Year: Issue:  4
Journal: OCCUPATIONAL HEALTH AND EMERGENCY RESCUE

Keyword:  HSP70乐果U87细胞细胞保护;
Abstract: 目的研究HSP70在乐果染毒U87细胞中的保护作用.方法预先给予细胞43℃热应激1 h,然后以浓度为100μmol/L的乐果对细胞分别进行4、8、16h染毒,染毒结束测AChE和SOD活性并与未经热应激诱导组比较.结果在不同染毒时间,预先经热应激处理的试验组,其AChE及SOD活性都较直接染毒的对照组高,差异有非常显著性(P<0.01),酶活性的变化率在不同时间组间的差异也具有非常显著性(P<0.01).结论预先进行热应激诱导对乐果染毒U87细胞具有保护作用.
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